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Any disruptionLow stomach acid (hypochlorhydria), parietal cell loss (atrophic gastritis), IF deficiency (pernicious anemia), or ileal disease (Crohns)can compromise absorption, leading to deficiency risk

Possible neural substrates of beer-craving in rats

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This was followed by a 35-day pharmacokinetic blood sampling and safety assessment period (i.e., 45 times the estimated cagrilintide t 1/2 ), with blood samples collected on days 8, 15, 22, 29 and 36